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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Biomol/Ursodeoxycholic Acid (sodium salt)/500 mg/Cay15121-500
产品编号:Cay15121-500
市  场 价:¥2600.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$130.00
品      牌: Biomol
公      司:Biomol
公司分类:
Biomol/Ursodeoxycholic Acid (sodium salt)/500 mg/Cay15121-500
商品介绍
Product information "Ursodeoxycholic Acid (sodium salt)"
Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA, Cay-10011286). UDCA is also a metabolite of lithocholic acid (LCA, Cay-20253) in human liver microsomes. It inhibits taurocholic acid (Cay-16215) uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 µM. UDCA (50 µM) inhibits apoptosis induced by deoxycholic acid (DCA, Cay-20756, Cay-18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.
Keywords: UDCA, (5beta)-3alpha,7beta-dihydroxy-cholan-24-oic acid, monosodium salt
Supplier: Cayman Chemical
Supplier-Nr: 15121-250

Properties

Application: Hydrophilic bile acid
MW: 414.6 D
Formula: C24H39O4 . Na
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 2898-95-5| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Caution Our products are for laboratory research use only: Not for administration to humans!
品牌介绍

五十多年来,Biomol一直是德国生命科学和生物技术产品的领先供应商之一。我们对生命科学研究的复杂理解从根本上与以下事实相关:我们公司是在同一时间成立的,现代生物医学时代已经开始。1960年代后期。

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